We just covered the 12 Best Stocks to Invest In According to Jim Simons’ Renaissance Technologies and Exelixis, Inc. (NASDAQ:EXEL) ranks 7th on this list.
Exelixis, Inc. (NASDAQ:EXEL) is another long-term holding in the 13F portfolio of Renaissance Technologies
The fund first disclosed a stake in the company back in the first quarter of 2011. This position comprised over 762,000 shares. By the middle of 2012, this stake had been sold off completely.
After buying and selling a stake in the firm two more times, the fund declared a new position in the company in the third quarter of 2016. Since then, the firm has featured consistently in the portfolio of the fund. Filings for the first quarter of 2026 show that the fund owned 13.7 million shares in the firm, down 1% compared to filings for the previous quarter.