The Invesco Biotechnology & Genome ETF (NYSEMKT:PBE) offers a focused, high-momentum approach to the biotechnology sector, while the Vanguard Health Care ETF (NYSEMKT:VHT) provides broad, low-cost exposure across the entire healthcare landscape — from pharmaceutical giants to…
uipment makers to healthcare providers. Snapshot (cost & size) Beta measures price volatility relative to the S&P 500; beta is calculated from monthly returns over the available fund history (up to five years)
The 1-year return represents total return over the trailing 12 months. Dividend yield is the trailing-12-month distribution yield. Cost is a major differentiator here.
VHT charges just 0.09% a year, versus 0.58% for PBE. The funds’ dividend yields are in the same ballpark, with VHT paying 1.58% and PBE paying 1.73% Performance & risk comparison What’s inside Launched in 2004, VHT uses a passive management approach to track the broader healthcare sector and holds 423 stocks. Its largest positions include Eli Lilly (NYSE:LLY) at 14.2%, Johnson & Johnson (NYSE:JNJ) at 8.9%, and AbbVie (NYSE:ABBV) at 6.5%.